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This is a technically detailed, up-to-date clinical reference on all the newest developments in management of the menopause. The contents include chapters on every important topic in this field, ranging from aging for men to estrogens and the cardiovascular system in the over 60s. It also covers hormone replacement therapy (HRT) with chapters on the brain, the central nervous system, hemostasis, stroke, the bladder and breast epithelial proliferation plus chapters on the menopause and tibolone therapy, the lower urinary tract, sexual functioning, breast cancer, hormone related cancer, obesity, and leptin levels. Other chapters deal with assessment, contraindications, oral and transdermal HRT, monitoring, depression, the endometrium, skeletal effects, and bisphosphonates.